Cloning and functional characterization of a family of human and mouse somatostatin receptors expressed in brain, gastrointestinal tract, and kidney
Viability, early apoptosis, and mortality assessment Following the manufacturers protocol, early apoptosis was assessed using Annexin V staining (Invitrogen, Thermo Fisher Scientific, Barcelona, Spain)
It works by activating three key hormone receptors: GLP-1 (glucagon-like peptide-1), GIP (glucose-dependent insulinotropic polypeptide), and the glucagon receptor
The most prominent changes revealed by the RNA-seq analysis include fat metabolism and stress response genes, consistent with previous transcriptomic analyses focusing on the glp-1(-) mutant 16
Reduced B12 levels will also contribute to impaired digestion, as this nutrient plays an important role in optimal gut health
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