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The ratio of reduced GSH to the disulfide form (GSH/GSSG) within the endoplasmic reticulum ranges from 1:1 to 4:1, whereas the overall cellular GSH/GSSG ratio ranges from 30:1 to 100:1 (Figure 2)

10.1371/journal.pone.0065300 203 ShuB.ZhangX.DuG.FuQ.HuangL

Moreover, the activities of other serum antioxidant enzymes in serum were assessed

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Results A total of 8,857 semaglutide 2.4 mg-treated patients were matched to 35,428 non-treated patients