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A very large fraction of published binding constants for melanocortin ligands, including those for cyclic analogues, peptidomimetics and candidate subtype-selective compounds, are reported as inhibition of I-NDP-alpha-MSH binding to membranes from cell lines stably expressing a single human receptor subtype

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Search strategy and selection criteria In this NMA study, relevant RCTs were retrieved in large databases including MEDLINE via PubMed, Embase, Web of Science, and Scopus, from inception to 26 July 2021

doi: 10.3389/fendo.2019.00508 Received 12 May 2019 Accepted 12 July 2019 Published 13 August 2019 Volume 10 - 2019 Edited by Giuseppe Biagini, University of Modena and Reggio Emilia, Italy Reviewed by Cara Jean Westmark, University of Wisconsin-Madison, United States

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