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Much of the modern enthusiasm for GHK-Cu traces to a body of gene-expression work suggesting the peptide can influence the activity of a very large number of human genes, with reviews describing modulation of thousands of gene sets involved in tissue remodeling, inflammation, and repair

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doi: 10.1016/j.scitotenv.2023.167043 182 HuCLiuMTangLLiuHSunBChenL

However, his experience also revealed a concerning pattern of lifestyle-related diseases where he noticed traditional treatments often fail to address the root cause

In osteosarcoma, MFAP2 drives EMT via activation of Notch1 signaling, enhancing migratory and invasive capabilities [56]