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Virtual ligand screening of the p300/CBP histone acetyltransferase: identification of a selective small molecule inhibitor
Poly(ADP-ribose) polymerases covalently modify strand break termini in DNA fragments in vitro
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Clinical studies would need to look into this benefit, though
We use evidence-based methods for dosages from 1 to 4 units
The IF staining and Western blot analyses for -H2AX, a marker for DNA double-strand damage, and phosphorylated nucleophosmin 1 (pNPM1) required for DNA damage repair were performed in RSL3-treated K1 cells
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