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A key target is the Kv7 (KCNQ) family of voltage-gated potassium channels

Selenium absorption occurs in the small intestine, with a recommended daily intake for adults of 55 mg/day ( Selenium deficiency can present with poor growth, loss of hair and skin pigmentation, muscle weakness and pain, cardiomyopathy, whitened nailbeds, and alterations in the immune system and anti-inflammatory response (354)

Facciol A, Visalli G, Lagan A, Di Pietro A

Mnch G, Brixius K, Frank K, Erdmann EWS

Oxidative damage to proteins, lipids, and DNA is evident in HD brain tissues, indicating the pervasive impact of oxidative stress