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In addition, using a time-dependent Cox regression analysis with SGLT2i use categorized by randomized treatment as a fixed factor yielded HRs for the primary outcome of 0.87 (95% CI, 0.711.06) for those using SGLT2i during the study (either from baseline or initiated during the study) and 0.83 (95% CI, 0.730.95) for those who never used SGLT2i throughout the study (Table S6)

Adv Exp Med Biol (2009) 643:4919

PMID: 11045725

Whether you are just starting out or adjusting your protocol, knowing how to calculate these numbers correctly is critical for safety and effectiveness

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