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Beclin 1ATG14L proteinprotein interaction inhibitor selectively inhibits autophagy through disruption of VPS34 complex I

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Over 19 days, 710GO was administered as an adjuvant with semaglutide to DIO NHPs, causing 7.6% weight loss compared to 4.1% when semaglutide was administered alone ( Importantly, 710GO does not demonstrate the cardiac liabilities observed with other melanocortin agonists

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