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The honest answer: it depends on the research question

doi: 10.1056/NEJMoa2313917 [DOI] [PubMed] [Google Scholar] 107.Monney M, Jornayvaz FR, Gariani K

A common approach is to load in March-April, maintain through summer, and stop in September

Liposomal glutathione is generally considered more effective because it protects the glutathione from being broken down by stomach acid

Melo AS, Ferriani RA, Navarro PA

In addition to the well-characterized catalytic activity, recent evidence has shown that certain GST isozymes can regulate mitogen-activated protein kinases or can facilitate the addition of glutathione to cysteine residues in target proteins ( S -glutathionylation)