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The intrinsic pathway is triggered by disruptions in the cellular microenvironment, demarcated by mitochondrial outer membrance permeabilization, and precipitated mainly by caspases 3 (Sanz et al., 2023)
Symptoms follow meals Flushing, congestion, headache, diarrhea or palpitations occur after aged, fermented or leftover foods
L-carnitine in health and disease: Drug, nutrient, and exercise interactions
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