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Meta-analysis reveals reproducible gut microbiome alterations in response to a high-fat diet

Efficacy estimand: This analysis was not included in the statistical testing hierarchy, and as such, is hypothetical and was not controlled for multiplicity Study design OASIS 4 7,10 : A randomized, double-blind, placebo-controlled 64-week trial of 307 adults with obesity (BMI 30 kg/m) or overweight (BMI 27 kg/m-29.9 kg/m) and 1 weight-related comorbid condition, such as treated or untreated dyslipidemia or hypertension

It also regulates blood sugar levels

While the two classes of medications provide similar benefits, they work differently, and experts say they work better when taken together

Akkermansia muciniphila Akkermansia muciniphila has emerged as one of the most-studied "next-generation probiotics" in metabolic health research

The inclusion of HOWARU Shape B420 - a trademarked strain with a published randomized controlled trial - distinguishes this formula from supplements using generic or unstudied probiotic strains