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In the TOGETHER-PsA trial, Merola and colleagues assessed the efficacy and safety of combination therapy with ixekizumab (Taltz, Eli Lilly) plus tirzepatide (Zepbound, Eli Lilly), compared with ixekizumab alone in a cohort of 271 adults with active PsA and overweight or obesity, aligned with the on-label dosing of both interventions

Central sensitization is considered a critical pathogenic mechanism of chronic migraine (CM)

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And the treatment can be delivered over a short course of time around 1-5 days rather than weeks or months

Myocardial infarction impairs renal function, induces renal interstitial fibrosis, and increases renal KIM-1 expression: implications for cardiorenal syndrome