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To ensure comparability with MRS-guided assessments, IHL content was calculated by fat/(water + fat) 100, including corrections for relaxation effects

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The risk varies by individual based on baseline B12 status, diet composition, and whether you have underlying conditions like pernicious anemia or metformin use (which also lowers B12)

Zhu H, Zhou L, Wang Q, Cai Q, Yang F, Jin H, Chen Y, Song Y, Zhang C (2023) Glucagon-like peptide-1 receptor agonists as a disease-modifying therapy for knee osteoarthritis mediated by weight loss: findings from the Shanghai Osteoarthritis Cohort

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Internally, the peptide is beginning to influence fat cell receptors and metabolic signaling