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doi:10.1007/s13311-012-0134-9 Hariprasad VR, Arasappa R, Varambally S, Srinath S, Gangadhar BN

mTORC1 hyperactivity underlies ASD in human diseases that are caused by mutations of genes that are upstream of mTORC1, such as tuberous sclerosis complex (13, 14) and PTEN tumor hamartoma syndrome (15)

24 Age-changes in GH secretory dynamics at later stages of life are clinically measurable as frank alterations of the earlier patterns that can be quantified by measurement of pulse timing and amplitude

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