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SubQ injections of more than 1mL of testosterone at a time is often discouraged

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These factors combine to create a perfect storm of digestive disruption in the first 2-4 weeks of treatment

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We propose that chronic exposure to a particular suite of environmental and genetic factors elicits a trajectory of impaired mitochondrial biology that maximally impacts subsets of mitotypes abundant in the brainstem and motor cortex, which eventually surfaces as the hallmark features of ALS

This shift is connected to the body metabolizing more fat, but it may be important in terms of safety, particularly for individuals with comorbidities