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Pancreatitis, pancreatic, and thyroid cancer with glucagon-like peptide-1-based therapies
Orforglipron, an oral small-molecule GLP-1 receptor agonist, for the treatment of obesity in people with type 2 diabetes (ATTAIN-2): a phase 3, double-blind, randomised, multicentre, placebo-controlled trial
She joined Merck Research Laboratories as a senior chemist in 1987
The combination of GLP-1R-mediated appetite suppression, GIPR-mediated adipose tissue metabolism, and GCGR-driven energy expenditure makes it one of the most comprehensive research tools for studying multi-pathway obesity biology in a single compound
Type 2 diabetes is usually accompanied by obesity and cardiovascular issues
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