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Notably, the CoQ 10 redox system represents a particularly attractive therapeutic node because multiple enzymatic pathways converge to maintain the cellular ubiquinol (CoQ 10 H 2 , reduced) pool

Different potential anchors were screened, and ultimately a series of lipids was identified that can direct the proteins to distinct membranes, such as the plasma membrane and endomembranes (ER and Golgi)

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While these drugs have gained popularity by helping people lose weight, up to 50% of consumers face gastrointestinal (GI) side effects