Int J Dermatol 60:451460
In addition, low molecular weight oligonucleotides are easier to deliver into the target cells compared with large viral vectors or plasmid normally used for gene therapy and are less likely to induce high immune response and toxicity as compared to plasmid DNA-based gene therapy and protein-based drug molecules (Li and Rana, 2014)
Basket trials : group patients by molecular subtype (e.g., LRRK2+ , SNCA+ , idiopathic)
High Performance Liquid Chromatography and Mass Spectrometry High Performance Liquid Chromatography-Mass Spectrometry analyses were performed on a Shimadzu Nexera UHPLC chromatograph interfaced with an Ab Sciex 3200 QTRAP mass spectrometer (AB SCIEX, Toronto, ON, Canada)
Hercberg et al., 1994
5-thio-2- nitrobenzoic acid has the largest absorption at wavelength of 412 nm, and 2-Vinylpyridine inhibit reduced glutathione in the original of samples, and then using glutathione reductase to reduce GSSG to GSH, determining the content of Oxidized Glutathione