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In summary, GLP-/GIP dual agonists have shown superior potential over GLP-1 in improving lipid metabolism

GLP-1 medications present a unique calcium concern

C., Tiuca, R

Additionally, patients with T2DM and comorbid cardiovascular or chronic kidney disease who received once-daily oral semaglutide (14 mg) exhibited a cardiovascular safety profile similar to that of the subcutaneous form [49]

In recent years, the regulator has specifically highlighted risks associated with counterfeit and falsified versions of GLP-1 receptor agonists, including semaglutide, and has extended its vigilance to newer investigational compounds being marketed prematurely to consumers

Others may need a slower titration, a dose adjustment, or a discussion about long-term medication strategy