Water, Butylene Glycol, Glycerin, Methylpropanediol, 1,2-Hexanediol, Niacinamide, Chlorella Vulgaris Extract, Cedrus Atlantica Bark Oil, Cynanchum Atratum Extract, Cananga Odorata Flower Oil, Althaea Rosea Flower Extract, Chitosan, Jasminum Officinale (Jasmine) Oil, Alpha-Arbutin, Propanediol, Allantoin, Glucose, Glutathione (1000 ppm), Tromethamine, Hydroxyacetophenone, Pentylene Glycol, Polyglyceryl-10 Isostearate, Ethylhexylglycerin, Caprylyl Glycol, Fructooligosaccharides, Fructose, Adenosine, Dipropylene Glycol, Polyglyceryl-10 Oleate, Hydrogenated Lecithin, Cholesterol, Ascorbic Acid, 3-O-Ethyl Ascorbic Acid, Ascorbyl Glucoside, Ceramide NP, Panthenol, Acetyl Hexapeptide-8, Ascorbic Acid Polypeptide, Acetyl Octapeptide-3, Acetyl Tetrapeptide-2, Acetyl Tetrapeptide-3, Acetyl Tetrapeptide-5, Acetyl Tetrapeptide-9, Carnosine, Copper Tripeptide-1, Nonapeptide-1, Palmitoyl Pentapeptide-4, Palmitoyl Tripeptide-1, Palmitoyl Tripeptide-5, Carbomer, Xanthan Gum, Disodium EDTA

Oxidation via CYP2E1 (5-10%) - TOXIC Creates NAPQI (N-acetyl-p-benzoquinone imine)the dangerous toxic metabolite INCREASES by 80% during pregnancy NAPQI measured at 43% HIGHER in first trimester when fetal brain is most vulnerable NAPQI must be immediately neutralized by glutathione When glutathione is depleted, NAPQI causes cellular damage Crosses placenta and damages fetal brain The Perfect Storm During Pregnancy Research reveals dramatic shifts in how pregnant women metabolize acetaminophen: Safe sulfation pathway DECREASES by 33% Toxic oxidation pathway INCREASES by 80% Glutathione levels DROP by 36-87% (when you need it most) Result: 43% MORE toxic NAPQI formed in first trimester Even though glucuronidation increases, it CANNOT compensate for the massive increase in toxic metabolite production combined with dramatically reduced glutathione reserves
18 Intranasal administration of reduced GSH, (in)GSH, could be an effective approach for delivery of GSH to the CNS
van Sloten, T
kvadratmeter r den genomsnittliga storleken p en bostadsrtt i Sverige Din webblsare stds ej lngre
What Is a Liposome