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Study 2: remote study Cohort characteristics We recruited 153 participants from various social media platforms to participate in our study

Anti-inflammatory drugs suppress proliferation and induce apoptosis through altering expressions of cell cycle regulators and pro-apoptotic factors in cultured human osteoblasts

| | 5-Amino-1MQ Monotherapy | None | 50100mg daily | Daily oral or subcutaneous | NNMT inhibition preserves NAD+, activates AMPK and mitochondrial fat oxidation | 812 weeks | Promising preclinical data

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10.1038/384173a0 Nature 202 XinX.YangS.IngleG.ZlotC.RangellL.KowalskiJ.et al (2001)