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GH release begins within 10 minutes of administration, peaks at 30-40 minutes, and returns to baseline by approximately 3 hours producing a single, clean GH pulse per dose

Adjustment Phase After the initial phase, the dose is usually increased to 5 mg once a week for 4 weeks, followed by a second increase to 7.5 mg once a week

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While TPOAb reflects an adaptive immune response, TgAb is more closely linked to innate immunity, representing distinct arms of the autoimmune reaction