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Unlike GHRP-6 and GHRP-2, which also stimulate appetite-regulating ghrelin and stress hormone cortisol, ipamorelin causes minimal changes in prolactin and cortisol levels

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However, the susceptibility of the sperm oxidase activity to the membrane impermeant thiol blocking agent pCMBS (p-chloromercuriphenylsulphonate) as well as retinoic acid, distinguishes the sperm-based activity from that detected in somatic cells [37]