Although few research institutions in this area can afford to use NHP models, the article provides new ideas for future work, such as combining single-cell sequencing technologies to screen differential gene expression in NHPs and carry out in vivo validations in rodents
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FIGURE 8 8 Thiols Glutathione (GSH) is an endogenous AT that is clinically useful
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The findings indicate that cerebral I/R injury not only causes a specific type of programmed neuronal death called PANoptosis but also triggers microglia to adopt a pro-inflammatory (M1) phenotype, both in living organisms and in vitro
eLife 10 , 67312 (2021)