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For preclinical tissue models, stronger evidence would require standardized injury models, blinded outcome assessment, histological confirmation, functional endpoints, and comparison against appropriate positive and negative controls

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Mid-portion tendinopathy typically responds faster than insertional problems due to easier injection access and slightly better baseline vascularity

They are better viewed as potential complements to conventional treatment, not substitutes

Collagen can also be taken on an empty stomach, though some prefer to mix it into a meal or a smoothie to make it part of a larger nutritional habit

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