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AOD-9604 was developed by Australian biotech company Metabolic Pharmaceuticals in the late 1990s as an attempt to isolate the fat-metabolizing properties of growth hormone without its growth-promoting effects

[2] Nicotinamide + SAM 1-MNA + SAH This reaction matters to researchers for two simple reasons

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International Journal of Obesity, 25(10), 1442-1449

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But before we get into how this new option works, lets look at the scope of the issue