In basal keratinocytes, the peptide increases integrin expression and enhances p63 positivity, a transcription factor that maintains stem cell characteristics
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this depletion of NAD + impairs cancer cell metabolism and may lead to cell death 229 (Fig
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Inflammopharmacology 30:20512061 De Felice FG (2013) Alzheimers disease and insulin resistance: translating basic science into clinical applications