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It participates in methyl transfer and folate metabolism in the body, and promotes the conversion of 5-methyltetrahydrofolate to tetrahydrofolate

Importantly, NNMT is a dominant component of the gene expression signature for sarcopenia, overexpression of which could lead to significantly reduced levels of NAD+ and associated declines in muscle mass, strength, and function that accompany aging

Evidence Snapshot What is MOTS-c vs 5-Amino-1MQ

Recognising this connection allows you to pay closer attention to how your skin responds when you start or adjust supplementation