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The study, A Study of Tirzepatide in Participants With Obesity or Overweight With Weight Related Comorbidities (SURMOUNT-5), has the primary outcome of percent weight change from baseline in body weight over a 72-week period

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2 Materials and methods 2.1 Protocol and registration This systematic review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement (Supplementary Table S1

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