Are Oral GLP-1s As Effective As Injections
For women, this matters even more
Semaglutide (Wegovy, Ozempic) aims at one receptor (GLP-1), while tirzepatide (Zepbound, Mounjaro) homes in on two (GLP-1 and GIP)
Retatrutide and Fat Targeting: Not Just Weight Loss Retatrutide influences how and where fat is lost, which is critical for long-term metabolic health
Appetite Regulation Pathways Due to its interaction with incretin-related receptors, retatrutide is being studied for its potential role in appetite signaling pathways in preclinical models
There is also a trial specifically testing whether retatrutide prevents heart attacks and strokes (TRIUMPH-3, 1,800 people), and a head-to-head trial comparing retatrutide directly against tirzepatide (the active ingredient in Zepbound) under identical conditions (NCT06662383, 800 patients)