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A 2022 systematic review and meta-analysis published in Frontiers in Endocrinology found that inositol supplementation significantly reduced BMI in women with polycystic ovary syndrome (PCOS), with a pooled weighted mean difference of -0.41 kg/m
This is for several reasons: Abundant subcutaneous tissue: The abdomen typically has sufficient subcutaneous fat tissue, even in lean individuals
Formulation alternatives may provide relief: Different tablet formulations with alternative inactive ingredients may be better tolerated Liquid preparations can be easier to tolerate and allow flexible dosing Intramuscular injections completely avoid the gastrointestinal tract and are particularly useful for those with absorption issues (such as pernicious anaemia or malabsorption) or persistent oral intolerance Review inactive ingredients: Examine the supplement label for potential irritants or allergens
Chemical and Physical Characteristics GHK-Cu is available in various salt forms, the acetate salt forms are thought to offer improved aqueous solubility, and some sources suggest good solubility of GHK-Cu up to 325mg/mL in water
No injection supplies
