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220-22, Okobi, Okelue E., et al

Clinical outcomes should be comparable when dosing matches the SURMOUNT trial protocols

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Researches showed that various monomers of medicinal plants by inhibiting key factors of lipid synthesis (SREBP-1c, FAS and ACC), promoting fatty acid oxidation (PPAR and CPT-1), improving insulin resistance, enhancing autophagy (ULK1 and LC3) and inhibiting inflammation (NF-B) and oxidative stress (Nrf2) (383)

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