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Differential requirement of the extracellular domain in activation of class B G protein-coupled receptors

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Thus GLP-1 was shown to regulate a number of diverse functions: reduction in digestive enzyme secretion, slowing of gastric motility, increases in heart rate and blood flow, increased bone remodeling, and suppression of appetite (via hypothalamic and brainstem nuclei)

Clinical Recommendations and Future Research Numerous retrospective studies have outlined the potential benefits of GLP-1RA on ocular disease