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10.1093/nar/gky1079 194 PaggiJ

doi:10.2337/db14-1947 44

Baseline kidney and cardiac assessment is essential, as semaglutide use in advanced age demands closer clinical oversight than in younger populations

Dec 1988;37(12):1595-1607

For example, senescent T-cells are accumulated in visceral adipose tissues in obesity 67 and produce proinflammatory cytokines, leading to chronic inflammation, metabolic disorders, and cardiovascular diseases 68,69