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Every participant met the clinical criteria for moderate to severe alcohol use disorder

Jonathan Reed, Lead Researcher of the study

Genetic Predispositions and Metabolic Markers Influencing Non-GLP-1 Response Genetic variations in appetite-regulatory genes, dopamine signaling, and lipid metabolism pathways influence how individuals respond to non-GLP-1 agents

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The biological drivers of appetite that were repressed by the medicines resurface, frequently leading to weight gain

Poor sleep can disrupt hunger hormones, making it harder to manage cravings