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[DOI] [Google Scholar] 11.Negrin A., Long C., Motley T.J., Kennelly E.J

Starting at low doses allows your body to tolerate the medication while your appetite center gradually adapts, preventing the intense nausea and gastrointestinal side effects that sometimes occur with rapid dose advancement

Dysfunctional brain insulin signaling has been shown using blood-neuron-derived extracellular vesicles, whereby PD patients display altered IRS1 phosphorylation, which is further correlated with tremor severity [158]

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