Studies indicate that emotional changes may be related to the medication's effects on brain regions involved in reward and motivation rather than direct mood alteration
As GLP-1 patents expire and Indian pharma giants launch generic versions, treatments once reserved for the affluent could become accessible to millions
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Telomeres are protective caps at the ends of chromosomes that shorten with each cell division
GLP-1 receptor agonists work by: Stimulating insulin secretion from pancreatic beta cells in a glucose-dependent manner, which helps regulate blood sugar levels Slowing gastric emptying , meaning food remains in the stomach longer, promoting feelings of fullness Acting on appetite centres in the brain , particularly the hypothalamus, to reduce hunger signals and food cravings Decreasing glucagon secretion , which helps prevent excessive glucose production by the liver Most GLP-1 agonists are administered via subcutaneous injection, typically once weekly or once daily depending on the specific formulation, though oral semaglutide (Rybelsus) is also available
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