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The deletion of the Stat3 gene increased the level of two cytolytic enzymes perforin and granzyme B in mouse NK cells and accordingly a lack of STAT3 signaling enhanced the NK cell-dependent tumor surveillance [119]

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Support was also received via Japan Agency for Medical Research and Development (AMED) Brain Mapping by Integrated Neurotechnologies for Disease Studies (Brain/MINDS) Grant Number JP18dm0207001 (TCS) and a research grant from the RIKEN Center for Brain Science

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These findings suggest that supersulfides play a crucial role in regulating the function of proteins across a wide variety of biological contexts