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Together these modifications dramatically reduce binding to IGF-binding proteins (IGFBPs), extending the free fraction half-life from approximately 10-15 minutes for native IGF-1 to roughly 20-30 hours for IGF-1 LR3

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Krishnaveni, G

This doesnt mean you cant touch the area, but you wouldnt want to lay on your face to have a massage, for instance, or wear a tightly-fitting motorcycle helmet - for those 36 hours directly after injection

It enhances fat oxidation meaning it helps the body burn fat more efficiently when conditions are right