This mechanism is similar to that of GLP-1 receptor agonists, but without the associated side effects
Research has focused on amylin receptor agonism (AMY1, AMY2, AMY3) and downstream effects on food intake, gastric emptying and energy homeostasis
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The risk for prolonged or permanent infertility following 2 years of therapy cessation is over 25% of patients on alkylating agents and in 20-47% of patients on platinum agents [16]