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Levels of marker gene expression in BPC-157-exposed and control cells were compared

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Yet decades later, researchers still do not have a clear understanding of how DSIP may work, whether it has a meaningful physiological role in humans, or whether the early findings represent a reproducible biological effect

Pro-apoptotic elements, BCL2 associated X, apoptosis regulator (BAX) and BCL2 antagonist/killer 1 (BAK1), drive processes such as mitochondrial outer membrane permeabilization and the creation of the mitochondrial permeability transition pore (MPTP), thus regulating the formation of pores in the outer mitochondrial membrane [112]

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