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The specific profile of inflammatory mediators dominant in endometriosis (high IL-1, IL-6, IL-8, TNF-, CCL2/MCP-1, MMPs) shows a striking resemblance to the canonical components of the SASP secreted by senescent cells [57]

Imiquimod is generally not recommended in invasive tumors or in young patients due to the risk of progression to invasive disease, or in patients who cannot be closely monitored.103,104 Response and Response-Related Factors Imiquimod applied 5 times a week for at least 12 weeks has been proposed as the most effective treatment regimen

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EMT is a critical biological process through which malignant tumor cells derived from epithelial cells acquire migratory and invasive capabilities

Additionally, it influences the upregulation of growth hormone receptors, which plays a pivotal role in tissue healing and regeneration

doi: 10.1007/s00005-010-0095-9 36 ChoiS.-r.BritiganB