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Placing IGF-1 LR3 vs IGF-1 side by side clarifies both what the engineering achieved and where the two molecules genuinely diverge

The first is confusing CJC-1295 with DAC and without DAC using a with-DAC dosing frequency for a without-DAC compound (or vice versa) produces either insufficient signal or wasteful overdosing

This metabolic transformation also results in reduced affinity of the compound for its cellular target