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99 Until more robust trials confirm their safety specifically in patients with reduced LVEF, GLP-1 RAs should be used cautiously in this population

A cohort study conducted in Denmark with 309,166 individuals diagnosed with diabetes revealed that treatment with GLP-1RAs led to a 50% decrease in amputations related to diabetes, when compared to those who did not receive GLP-1RA treatment [78]

Tirzepatide injections mimic the action of two essential hormones: GLP-1 and GIP

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- Mayor saciedad, lo que reduce el consumo de caloras

The first to file in the US gets a 180-day period of exclusivity during which it can be the sole marketer of the generic version