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Pharmacological synergistic effects of SGLT2 inhibitors in DKD therapy Monotherapy with metformin, insulin or pioglitazone alone is poorly effective in maintaining long-term glycemic control and renoprotection in a majority of patients with DKD [41]

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Semaglutide, a glucagon-like peptide-1 (GLP-1) receptor agonist, has transformed weight management for millions of people seeking sustainable fat loss without extreme calorie restriction

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