doi: 10.1093/ajcn/77.6.1352 49 BellIRMorrowFDReadMBerkesSPerroneG
In 28-month-old mice, roughly equivalent to elderly humans, three weeks of GHK-Cu administration produced significantly faster maze navigation with evidence of decreased brain inflammation and increased histone deacetylase 2 labeling, an indicator of epigenetic pathway activation
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Unfortunately, this can result in poor outcomes for patients who have to deal with ongoing pain, discomfort, and follow-up procedures
Another anticancer candidate, STP707, is currently being evaluated in a Phase I trial (NCT05037149) for safety, tolerability, and anti-tumor activity in participants with advanced/metastatic or surgically unresectable solid tumors
Although it does not have any carcinogenic and teratogenic effects, it is not recommended for use during pregnancy and lactation periods due to lack of sufficient evidence