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For instance, LAS17, one of the most effective known inhibitors, has an IC 50 of 500 nM and works by covalently binding to tyrosine residues on GSTP1 (Louie et al

The tolerable upper intake level set by the Institute of Medicine is 100 mg per day for adults, and the compounded dose is a small fraction of that

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On one hand, it is reassuring in the trivial sense: the community converged on doses below the studied range, not above it

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