In a cohort study that was conducted in 2024 using TriNetX network, semaglutide was not associated with an increased risk of NAION in patients with type 2 diabetes compared with non-GLP-1RA antidiabetic medications but had an HR of 2.32 (95% CI, 0.60-8.97)
Hunger hormones return to normal levels, metabolism adjusts, and digestion speeds up
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Thats essentially the basic mechanism of a GLP-1. In most cases, these drugs will need to be taken permanently to keep the weight off
Dose escalation should proceed gradually to minimize discomfort and allow the digestive system to adjust
NICE guidance (NG3) on diabetes in pregnancy includes postnatal management recommendations, advising that insulin and/or metformin are the preferred options for breastfeeding mothers with diabetes, while other agents should generally be avoided