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Biochemical modulators of tight junctions (TJs): occludin, claudin-2 and zonulin as biomarkers of intestinal barrier leakage in the diagnosis and assessment of inflammatory bowel disease progression

Delaying gastric emptying

The glutathione disulfide (GSSG) formed can be recycled to GSH by glutathione reductase in the presence of NADPH

The most commonly reported adverse effects are gastrointestinal in nature , affecting a significant proportion of patients, particularly during the initial weeks of treatment or following dose escalation

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