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Studies suggest that further molecular characterization is required to elucidate the peptide's precise support within a research model

The brain regions (e.g., NST) responsible for mediating the inhibitory effect of GLP-1 on gastric emptying depend on intact vagal afferent input

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PEX-168 is a new agent of long-acting GLP-1R agonist, which is molecularly modified from EX via amino acid modification and PEGylation (119), the first GLP-1R agonist modified by PEG to achieve long-term pharmacological action (120, 121)